Celastrol CAS 34157-83-0

CAS:34157-83-0

Cov mis molecular:C29H38O4

Qhov Hnyav Molecular:450.61

EINECS:636-472-5

Cov lus txhais:CELASTROL(SH); CELASTROL; Celastrol (Tripterin); CELASTROL(P)(THOV HU RAU); (20R)-3-Hydroxy-2-oxo-24-nor-D:A-friedoolean-1(10),3,5,7-tetren-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedela-1(10),3,5,7-tetraene-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedelane-1(10),3,5,7-tetraene-29-oic acidCelasterol

Sau Koj Cov Lus

Cov Khoom Qhia Txog Khoom

Rub tawm

Cov Cim Npe Khoom

Celastrol CAS 34157-83-0 yog dab tsi?

Celastrol tsis yaj hauv dej, yaj hauv dimethyl sulfoxide thiab anhydrous ethanol. Tau los ntawm cov khoom xyaw tiv thaiv kab mob qog noj ntshav hauv cov nroj tsuag xws li Thunder God Vine thiab South Snake Vine hauv tsev neeg Celastraceae. Ib qho tshuaj proteasome inhibitor zoo, tau lees paub tias ua rau cov hlwb qog noj ntshav tuag los ntawm kev txwv tsis pub ua haujlwm proteasome.

Cov Lus Qhia Tshwj Xeeb

Khoom	Cov Lus Qhia Tshwj Xeeb
Kub taw tes	645.7±55.0 °C (Kwv yees)
Qhov Ceev	1.2
Qhov kub yaj	219-230°C
pKa	4.78 ± 0.70 (Kwv yees)
λmax	424nm (MeOH) (lit.)
Cov xwm txheej cia khoom	-20°C

Daim Ntawv Thov

Celastrol siv rau kev txiav txim siab cov ntsiab lus / kev txheeb xyuas / kev sim tshuaj, thiab lwm yam. Cov teebmeem tshuaj: Nws muaj cov khoom muaj zog antioxidant, cov teebmeem tiv thaiv mob qog noj ntshav angiogenesis, thiab cov teebmeem tiv thaiv rheumatoid. Ib qho tshuaj proteasome inhibitor zoo, tau lees paub tias ua rau cov hlwb qog noj ntshav apoptosis los ntawm kev txwv tsis pub muaj proteasome.