Sodium Stearyl Fumarate CAS 4070-80-8

CAS:4070-80-8 : kuv

Molecular Formula:C22H41NaO4

Molecular Luj:392.56 ib

EINECS:223-781-1 : kuv

Synonyms:sodium ntsev; SODIUMMONO-STEARYLFUMARATE; Sodium stearyl 2-fumarate; Sodium stearyi fumarate; SODIUM STEARYL FUMARATE; sodium octadecyl fumarate

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Sodium Stearyl Fumarate CAS 4070-80-8 yog dab tsi?

Sodium Stearyl Fumarate yog cov hmoov dawb zoo. Soluble hauv methanol, yuav luag insoluble hauv dej. Sodium Stearyl Fumarate yog tau los ntawm reacting stearic cawv nrog maleic anhydride, isomerizing cov tshuaj tiv thaiv cov khoom rau hauv ntsev. Sodium Stearyl Fumarate yog hydrophilic lubricant siv los ua cov roj nplua nyeem hauv cov tshuaj excipients. Nws tuaj yeem kov yeej ntau yam teeb meem ntsig txog magnesium stearate, xws li cuam tshuam rau cov tshuaj tseem ceeb thiab lubrication ntau dhau; Kev tsim cov yeeb yaj kiab tiv thaiv hauv cov ntsiav tshuaj effervescent tuaj yeem txhim kho kev sib cais, txhawb kev sib cais, thiab yog li ua kom bioavailability.

Specification

Yam khoom	Specification
melting point	≥196 ° C (lub kaum hli ntuj)
Cia tej yam kev mob	Inert cua, Chav Kub
kev huv	98%
LogP	8.789 (ib.)
xim	Dawb mus rau dawb

Daim ntawv thov

Sodium stearate fumarate (C22H39NaO4) yog ib qho khoom siv dav siv thiab tseem ceeb ntawm cov tshuaj thiab zaub mov. Thaum lub sij hawm metabolic txheej txheem ntawm sodium fumarate nyob rau hauv cov tsiaj, feem ntau ntawm nws yuav absorbed thiab hydrolyzed los tsim stearic cawv thiab stearic acid. Ib feem me me tuaj yeem ncaj qha thiab sai sai metabolized, thiab nws tsis muaj tshuaj lom thiab tsis khaus. Hauv kev lag luam tshuaj, sodium stearate fumarate yog ntxiv rau cov tshuaj formulations raws li lub roj nplua nyeem rau cov ntsiav tshuaj thiab tshuaj ntsiav. Chemicalbook kuj tseem tuaj yeem tsim cov yeeb yaj kiab tiv thaiv hauv cov ntsiav tshuaj effervescent, uas tuaj yeem daws cov teeb meem ntawm stearate lubricants thiab txhim kho cov tshuaj disintegration thiab txhawb cov tshuaj dissolution. Hauv kev lag luam khoom noj khoom haus, FDA tso cai rau sodium fumarate stearate ncaj qha ntxiv los ua tus tswj hwm thiab stabilizer rau cov zaub mov npaj rau tib neeg noj, xws li ntau yam khoom ci, hmoov nplej thickened, qos yaj ywm qhuav, thiab cov nplej ua tiav. Tus nqi ntawm sodium fumarate ntxiv tuaj yeem suav txog 0.2-1.0% ntawm qhov hnyav ntawm cov khoom noj.