SHIKONIN CAS 517-89-5

CAS: 517-89-5

synonyms:

5,8-Dihydroxy-2-[(R)-1-hydroxy-4-methyl-3-pentenyl]-1,4-naphthalenedione; TokyoViolet;(R)-5,8-Dihydroxy-2-(1-hydroxy -4-Methylpent-3-en-1-yl)naphthalene-1,4Chemicalbook-dione;SHIKONIN(AS);Shikonin,froMARnebiasp.;(-)-ShikoninChina;Shikonine;Shikonin5,8-Dihydroxy-2-[(1R )-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione

Hom Lub Npe: Unilong
Qhov chaw ntawm Keeb Kwm: Shandong, Suav
Purity: 99%

Khoom npe: SHIKONIN

Ntim: 25kgs / nruas

Kev xa khoom: Tam sim ntawd

MF: C16H16O5

MW: 288.3

Tso Koj Cov Lus

Product Detail

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Khoom cim npe

Dab tsi yogSHIKONIN

Ntshav-xim av koob siv lead ua, melting point 147 ℃, optical rotation αD20 = + 135 ° (benzene). Soluble nyob rau hauv phenethyl ether, acetone, chloroform, methanol, ethanol, glycerol, tsiaj thiab zaub roj thiab alkaline aqueous daws, insoluble nyob rau hauv dej. Cov xim hloov pauv nrog tus nqi Ph, nrog tus nqi Ph ntawm 4-6 yog liab, Ph tus nqi ntawm 8 yog ntshav, thiab Ph tus nqi ntawm 10-12 yog xiav. Lub teeb pom kev zoo, tiv thaiv tshav kub thiab oxidation tsis kam, tsis ruaj khov rau txo cov koob tshuaj, thiab tsaus liab doog nyob rau hauv cov ntaub ntawv ntawm hlau ions. Nws muaj cov nyhuv antibacterial.

Specification ntawmSHIKONIN

CAS	517-89-5 : kuv
Lwm Lub Npe	Shikonine
Qhov tshwm sim	ntshav hmoov
Purity	99%
Xim	ntshav liab
Cia	Txias Dried Cia
Pob	25kg / hnab
Daim ntawv thov	Khoom noj khoom haus

Daim ntawv thov ntawmSHIKONIN

(1) Cov nyhuv hypoglycemic Cov nplooj extract ntawm comfrey thiab polysaccharide (A, B, C) ntawm comfrey muaj cov nyhuv hypoglycemic.

(2) Cov nyhuv Bacteriostatic Lithospermum muaj cov nyhuv inhibitory ntawm Jingke 68-1 tus kab mob hauv vitro, thiab muaj cov nyhuv inhibitory ntawm Staphylococcus aureus. Cov nyhuv anti-parainfluenza ntawm levoshikonin tau kawm los ntawm hemagglutination cov tshuaj tiv thaiv thiab cytopathic txoj kev. Cov txiaj ntsig tau pom tias nws muaj cov tshuaj toxicity tsawg nyob rau hauv cov concentration ntau yam siv hauv kev sim, thiab muaj qee yam hauv vitro tiv thaiv kab mob khaub thuas ua haujlwm thiab tua tus kab mob parainfluenza ncaj qha. nyhuv.

(3) Kev cuam tshuam rau cov ntshav coagulation: Intraperitoneal txhaj tshuaj ntawm shikonin Cheebtsam (shikonin, acetylshikonin) tsis cuam tshuam rau cov ntshav coagulation lub sij hawm, tab sis tuaj yeem tiv thaiv cov nyhuv anticoagulant ntawm heparin.

(4) Anti-tumor effect Comfrey extract muaj qee yam inhibitory nyhuv ntawm theem lig (G2 theem) ntawm DNA synthesis hauv Hela hlwb.

(5) Antitumor nyhuv Shikonin inhibits proliferation, txhawb apoptosis thiab induces cell voj voog ntes nyob rau hauv cultured human choriocarcinoma tshuaj-resistant cell kab (JAR / MTX) nyob rau hauv vitro. Cov kev sim qhia tau hais tias qhov concentration ntawm shikonin nce nrog cov koob tshuaj. Thiab lub sijhawm ntev ntawm qhov kev txiav txim, qhov inhibition tus nqi ntawm kev loj hlob ntawm choriocarcinoma tshuaj tiv thaiv hlwb kuj nce ntau.

(6) Kev cuam tshuam ntawm cov tshuaj hormone secretion Cov nyhuv ntawm shikonin ntawm kev ua haujlwm ntawm hypothalamic-pituitary-gonadal axis hauv cov hluas poj niam nas pom tau tias cov qib tshuaj hormones hauv pawg shikonin tau qis dua cov hauv pawg tswj tsis zoo, thiab muaj tsis muaj qhov sib txawv tseem ceeb piv nrog rau pawg tswj hwm zoo. txawv. Nws qhia tau hais tias shikonin tuaj yeem cuam tshuam kev ua haujlwm ntawm hypothalamic-pituitary-gonadal axis hauv nas.

(7) Cov nyhuv Antioxidant Qee cov kws tshawb fawb tau ntsuas qhov muaj peev xwm ntawm shikonin rau superoxide radical (O2-) thiab 1,1-diphenyl-2-picrophenhydrazine radical (DPPH), thiab nws cov nyhuv ntawm β- - Inhibition ntawm carotene / linoleic acid autoxidation qhov system. Cov txiaj ntsig tau pom tias shikonin muaj peev xwm tshem tawm tau zoo rau DPPH thiab O2-, thiab muaj qhov pom tseeb inhibitory cuam tshuam ntawm nws pib-oxidation system ntawm β-carotene / linoleic acid. Muaj zog antioxidant muaj peev xwm.