Metronidazole CAS 443-48-1

CAS:443-48-1 : kuv

Molecular Formula:C6H9N3O3

Molecular Luj:171.15 Nws

EINECS:207-136-1 : kuv

Synonyms:TIMTEC-BB SBB001486; 1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole; 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(beta-Hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(beta-Oxyethyl)-2-methyl-5-nitroimidazole; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-; 1-Hydroxyethyl-2-methyl-5-nitroimidazole; 2-(2-Methyl-5-nitro-1H-imidazol-1-yl) ethanol; 2-Methyl-1-(2-hydroxyethyl)-5-nitroimidazole

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Metronidazole CAS 443-48-1 yog dab tsi?

Metronidazole yog dawb los yog daj me ntsis crystalline los yog crystalline hmoov; Muaj ib tug me ntsis tsw, nrog ib tug iab thiab me ntsis salty saj. Me ntsis soluble hauv ethanol, me ntsis soluble hauv dej los yog chloroform, thiab me ntsis soluble hauv ether. Metronidazole yog ib qho nitrogen-muaj heterocyclic compound nrog alkalinity thiab dej solubility tsawg. Raws li txoj cai prodrug, metronidazole yog tsim los rau hauv cov poov tshuaj phosphate ester, uas ua rau kom nws cov dej solubility thiab tuaj yeem siv los ua cov tshuaj txhaj tshuaj.

Specification

Yam khoom	Specification
Boiling point	301.12°C (kev kwv yees kwv yees)
Qhov ntom	1.3994 (zeeg)
Melting point	159-161 ° C (lit.)
pKa	pKa 2.62 (H2O, t = 25 ± 0.2,
Cia tej yam kev mob	2-8 ° C

Daim ntawv thov

Metronidazole muaj cov tshuaj tua kab mob muaj zog rau feem ntau cov kab mob anaerobic thiab siv los kho cov kab mob amoebiasis, trichomoniasis, thiab kab mob anaerobic. Nws kuj yog siv los kho qhov chaw mos trichomoniasis thiab tau siv rau hauv plab hnyuv thiab extraintestinal amoebiasis txij thaum 1970. Nws cov nyhuv yog siab, toxicity yog tsawg, thiab nws yog dav siv. Muaj mutagenic thiab teratogenic cuam tshuam rau cov tsiaj sim.